Total Antioxidant Activity, Total Phenolic Content And Radical Scavenging Activity Both Flesh And Peel Of Red Pitaya, White Pitaya And Papaya

Rohin, Mohd Adzim Khalili and Abu Bakar, Che Abdullah and Ali, Abdul Manaf (2012) Total Antioxidant Activity, Total Phenolic Content And Radical Scavenging Activity Both Flesh And Peel Of Red Pitaya, White Pitaya And Papaya. International Journal of Pharmacy and Pharmaceutical Sciences, 4 (2). pp. 113-122. ISSN 0975-1491

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Abstract

Red pitaya is known to have a number of nutritional benefits, including cholesterol-lowering effects, protection against diabetes and cancer. The objectives of this study was to evaluate total antioxidant capacity, total phenolic content and radical scavenging activity of both flesh and peel of red pitaya, white pitaya and papaya of the hexane, dichloromethane (DCM), ethyl acetate (EA) and methanol extracts. Based on the results obtained, the tested fruit extracts showed strong antioxidant activity or differential capacity to inhibit lipid peroxidation by FTC and TBA method which is indicated by their low absorbance values. At a given concentration, the relatively higher activity was recorded in the extracts of red pitaya flesh followed red pitaya peel, white pitaya flesh, white pitaya peel, papaya flesh and papaya peel, surpassing the activity of standard commercial antioxidant, α-tocopherol and BHT. Red pitaya flesh showed low radical scavenging activity as compared to BHA but greater than BHT and α- tocopherol, showing that red pitaya flesh contained high amount of radical scavenging compounds. Red pitaya flesh also showed the highest reductive activity as compared with white pitaya flesh, papaya flesh, red pitaya peel, white pitaya peel and papaya peel. The fruit flesh extracts activities were lower than α-tocopherol, BHA and BHT standards and these differences were statistically very significant (p<0.05). Superoxide radical scavenging activity of those samples followed the order: BHA>BHT>α-tocopherol>red pitaya flesh> white pitaya flesh>papaya flesh>red pitaya peel> papaya peel>white pitaya peel. Red pitaya flesh showed low radical scavenging activity as compared to BHA but greater than BHT and α-tocopherol, showing that red pitaya flesh contained high amount of radical scavenging compounds.

Item Type: Article
Keywords: Antioxidant activity, TBA, FTC, DPPH, Phenolic compound and chelating activity.
Subjects: R Medicine > RS Pharmacy and materia medica
Faculty / Institute: Faculty Of Health Sciences
Depositing User: Dr Mohd Adzim Khalili Rohin
Date Deposited: 19 May 2014 04:47
Last Modified: 28 Apr 2015 06:28
URI: http://erep.unisza.edu.my/id/eprint/919

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