FRSA and Cytotoxic and Antimitotic Potential of Solanum nigrum and torvum.

Rao , U.S. Mahadeva (2013) FRSA and Cytotoxic and Antimitotic Potential of Solanum nigrum and torvum. Discussion Paper. LAP Lambert Academic Publishing, Germany.

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Abstract

Background: Solanum nigrum and torvum are biologically-active compounds which when in defined qualitative as well as quantitative amounts provides a clinically proven and documented health benefit, and thus, an important source in the prevention, management and treatment of chronic diseases of the modern age". Objectives: This monograph encompasses with to screen the phytochemicals and to assess the comparative superoxide radical scavenging and reducing potency of leaves of Solanum nigrum or Black nightshade, as well as to evaluate the cytotoxic and antimitotic activities of Solanum nigrum using MCF-7 cell lines. Nevertheless, this study is extended further to evaluate the phytochemicals and free radical scavenging efficacy of different parts (dry leaves, dry fruits and fresh fruits) of Solanum torvum or turkeyberry, in addition to evaluate the activity of the extract of Solanum torvum on MCF-7 cell lines towards prevention of cancer. Conclusion: Both the herbal extracts are having promising phytonutrients that could be exploited against oxidative stress, cancer, ageing, ischemic heart disease in dissolving thrombus, microbial infections and hormone replacement therapy justifying their use in traditional medicine as nutraceuticals. Key words: Solanum nigrum; Solanum torvum; Turkeyberry; Oxidative stress; Cancer; Functional food; Nutraceuticals.

Item Type: Monograph (Discussion Paper)
Subjects: R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
R Medicine > RM Therapeutics. Pharmacology
Faculty / Institute: Faculty of Medicine
Depositing User: Dr U.S.Mahadeva Rao
Date Deposited: 15 May 2014 02:29
Last Modified: 28 Apr 2015 02:54
URI: http://erep.unisza.edu.my/id/eprint/771

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