Association of smoking with blood lipids in coronary heart disease patients admitted in Taiping Hospital, Perak, Malaysia

Haque, A. T. M. Emdadul and Kamaruzzaman, Shah Reza Bin and Haque , Mainul (2016) Association of smoking with blood lipids in coronary heart disease patients admitted in Taiping Hospital, Perak, Malaysia. Medical Journal of Dr. D.Y. Patil University, 9 (1). pp. 36-42.

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Abstract

Introduction: Cigarette smoking is one of the predisposing factors for cardiovascular diseases as it may increase lowdensity lipoproteins (LDLs) levels and decrease high-density lipoproteins (HDLs). Objective: To measure the blood level of LDL and HDL and compare the result between smokers and nonsmokers who suffered from coronary heart diseases (CHDs). Materials and Methods: This is a cross-sectional study. The information was collected by using a checklist from the records of CHD patients, admitted to Taiping General Hospital, Perak, Malaysia. Data collected were interpreted to find any significant association between smoking, level of total cholesterol, triglycerides, HDL, and LDL. Results: Among the 196 patients included in this study, 85 were active smokers (43.4%), 54 exsmokers (27.6%), and 57 nonsmokers (29%). Out of 171 patients with decreased level of HDL, 90.6% were smokers, 88.9% exsmokers, and 80.7% of nonsmokers. It was found that significant changes occurred among the groups with decreased level of HDL (P < 0.05). Conclusion: HDL level is more reduced among the smokers compared to the ex-smokers and nonsmokers especially in the female

Item Type: Article
Keywords: Coronary heart diseases, lipid profile, Malaysia, smoking Access this article online Quick Response Code: Website: www.mjdrdypu.org DOI: 10.4103/0975-2870.172426 vasculature can be due to a number of factors. One of the most important is cigarette smoking. Tobacco can predispose to plaque formation through inflicting injury to the blood vessels by decreasing high-density lipoprotein-cholesterol (HDL-C) and increasing low-density lipoprotein-cholesterol (LDL-C).[7] Plaque formation is one of the major predisposing factors of CHD and it can cause thickening of the arterial wall (atherosclerosis).[8] Thickened and narrowed blood vessels lead to depletion of blood supply to the heart. The oxygen demanding heart will infarct as the oxygen supply cannot meet the oxygen requirement.[9] Some studies were done to identify the risk factors for the development of CHD that was a leading cause of death and disability in both developed and developin
Subjects: R Medicine > R Medicine (General)
Faculty / Institute: Faculty of Medicine
Depositing User: Professor Dr Mainul Haque
Date Deposited: 03 Jan 2016 03:40
Last Modified: 03 Jan 2016 03:40
URI: http://erep.unisza.edu.my/id/eprint/4341

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