Phoenix dactylifera Linn as a potential novel anti-oxidant in treating major opioid toxicity

Haruna Sani, Ibrahim and Abu Bakar, Nor Hidayah and Rohin, Mohd Adzim Khalili and Suleiman, Ibrahim and Ibrahim Umar, Maryam and Mohamad, Nasir (2015) Phoenix dactylifera Linn as a potential novel anti-oxidant in treating major opioid toxicity. Journal of Applied Pharmaceutical Science, 5 (8). pp. 167-172. ISSN 2231-3354

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Abstract

The use of opioid has gain popularity in the field of medicine especially in treating chronic terminally ill patients. Unfortunately, several adverse effects in relation to its use have been reported. Literature search on the adversity of opioid in treating pain, its paradoxical hyperalgesic effects and susceptibility to addiction were conducted using Pubmed, Embase and Google Scholar without species limitation. This brief article focuses on the corresponding neuro-protective, hepato-protective, anti-inflammatory, ulcero-protective and nephron-protective functions of Phoenix dactylifera L to elaborate on evidences, mechanisms, modulatory and pharmacological significance to counteract adverse effects of opioid treatment and provide insight on the underlying mechanisms of addiction.

Item Type: Article
Keywords: Phoenix dactylifera L, opioids, neuro-protective, hepato-protective and nephro-protective.
Subjects: R Medicine > RZ Other systems of medicine
Faculty / Institute: Faculty of Medicine
Depositing User: Dr Nor Hidayah Abu Bakar
Date Deposited: 28 Oct 2015 07:09
Last Modified: 28 Oct 2015 07:09
URI: http://erep.unisza.edu.my/id/eprint/3824

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