Correlation of SerumErythropoietin and Ferritin Levels with the Frequency of Blood Donation

Fouz AA, Abdul Aziz and Abdullah, Uday Younis Hussein and A Rahim, Norhaza (2014) Correlation of SerumErythropoietin and Ferritin Levels with the Frequency of Blood Donation. Journal of Blood Disorders and Transfusion, 5 (8). p. 4. ISSN 2155-9864

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Abstract

Aim: The objective is to assess the correlation of serum ferritin and erythropoietin levels with the frequency of donation among blood donors in Pulau Penang, Malaysia. Methods: One hundred and forty-seven (108 male and 39 female) voluntary whole blood donors whom donating blood at the Blood bank, Hospital Pulau Pinang were included. For each donor, haemoglobin, serum ferritin and erythropoietin (EPO) assay were done. Laboratory works had been done at the Advanced Diagnostic Laboratories (ADL), Advanced Medical and Dental Institute (AMDI), Universiti Sains Malaysia (USM). Results: A signiicantly increased (p=0.014) serum ferritin was found in the irst time donor (105.3 ng/ml) compared to regular donors (69.3 ng/ml) who had donate blood more than once in the preceding year of both gender. The larger amount of donated blood in regular male donor results in a more risk of latent iron deiciency compared to female counterpart. EPO was signiicantly higher while ferritin was signiicantly lower in regular donors than in the control. The serum EPO showed a statistically signiicant inverse relationship with ferritin level and this relationship was signiicantly correlated. Conclusion: Adequate daily, oral iron supplementation at post donation would need to be provided for 90 days, which is longer than most current recommended iron replenishment programs together with the introduction of serum ferritin assay at irst donation and annually for regular donors to increase the safety of national blood supply recommended.

Item Type: Article
Subjects: R Medicine > RB Pathology
Faculty / Institute: Faculty of Medicine
Depositing User: AP Dr. Uday Younis Hussein Hussein
Date Deposited: 07 Jan 2015 06:23
Last Modified: 28 Oct 2015 01:17
URI: http://erep.unisza.edu.my/id/eprint/2883

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