Inhibitory effect of asiatic acid on acetylcholinesterase, excitatory post synaptic potential and locomotor activity

Mat Nor, Mohd Nasir (2012) Inhibitory effect of asiatic acid on acetylcholinesterase, excitatory post synaptic potential and locomotor activity. Phytomedicine, 19 (3-4). pp. 311-316. ISSN 0944-7113

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Abstract

The asiatic acid, a triterpenoids isolated from Centella asiatica was used to delineate its inhibitory effect on acetylcholinesterase (AChE) properties, excitatory post synaptic potential (EPSP) and locomotor activity. This study is consistent with asiatic acid having an effect on AChE, a selective GABAB receptor agonist and no sedative effect on locomotor.

Item Type: Article
Keywords: Centella asiatica, Asiatic acid, Acetylcholinesterase, Excitatory postsynaptic potential, Locomotor activity
Subjects: R Medicine > RM Therapeutics. Pharmacology
Faculty / Institute: Faculty of Medicine
Depositing User: Mr Mohd Nasir Mat Nor
Date Deposited: 06 May 2014 08:11
Last Modified: 28 Apr 2015 04:53
URI: http://erep.unisza.edu.my/id/eprint/278

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