Antimicrobial Effect of Separate Extract of Acetone, Ethyl Acetate, Methanol and Aqueous from Leaf of Milkweed (Calotropis gigantea L.)

M. , Hemalatha and B. , Arirudran and U.S , Mahadeva Rao (2011) Antimicrobial Effect of Separate Extract of Acetone, Ethyl Acetate, Methanol and Aqueous from Leaf of Milkweed (Calotropis gigantea L.). Asian Journal of Pharmaceutical Research , 1 (4). pp. 102-107. ISSN 2231-5683 (Printed) 2231-5691 (Online)

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Abstract

Objective: The present communication attempts to study the antimicrobial activity of leaf of Calotropis gigantea L. Methods: The leaf is subjected to various extraction using acetone, ethyl acetate, methanol and aqueous solvents against different bacterial and fungal organisms using disc diffusion method. Result: The acetone, ethyl acetate, methanol and aqueous extracts were active against all the samples and showed significant antibacterial properties. The methanol, acetone, ethyl acetate and aqueous extracts exhibited less activity against fungal organisms. Conclusion: Thus it may be suggested that leaf extracts of Calotropis gigantea L. may be used to treat oral bacterial diseases. KEYWORDS: Calotropis gigantea L, Antimicrobial activity, Disc diffusion method.

Item Type: Article
Subjects: Q Science > QR Microbiology > QR355 Virology
Faculty / Institute: Faculty of Medicine
Depositing User: Dr U.S.Mahadeva Rao
Date Deposited: 08 Feb 2015 04:30
Last Modified: 28 Apr 2015 06:36
URI: http://erep.unisza.edu.my/id/eprint/2248

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